Frequently (and not so frequently) Asked Questions
BRIEF: Could you help me find a website on the critical effects and target organs for non-carcinogens?
QUESTION:
Can anyone direct me towards a source (hopefully on the net) which
identifies the critical effects and target organs for s. I
have gleaned what I can from the IRIS database, but need more information
for a risk assessment (i.e., segregation of hazard indices).
ANSWER:
The EDF Chemical Scorecard provides lists of chemicals that have been
associated with various noncancer health effects by a variety of published
sources, with full references to the source making the hazard
identification.
See http://www.scorecard.org/health-effects/ if you want a list of
chemicals by endpoint
See http://www.scorecard.org/chemical-profiles/ if you want to search for
endpoints for a specific chemical
If your specific interest is defining the set of chemicals that should be
considered for estimating a cummulative hazard index for a specific
noncancer health effect, the best guidance I am aware of has been developed
by CalEPA:
CalEPA, Office of Environmental Health Hazard Assessment.
Draft Technical Support Document for the Determination of
Noncancer Chronic Reference Exposure Levels (10/97)